Sculptor

Sculptor is an interactive multi-resolution docking and visualization program for low-resolution density maps and atomic structures. We are developing Sculptor as a GUI-based extension of the Situs docking programs, to allow an interactive exploration and analysis of volumetric maps. Sculptor combines 3D rendering with advanced mathematical concepts like clustering techniques and pattern matching algorithms to permit an almost instantaneous fitting of the high-resolution structures and to facilitate typical post-processing work like map editing or resolution adjustment.

Participation

Research directly related to Sculptor will be presented at the following conferences:

Invited talk: 52th Annual Meeting, Biophysical Society,
Sculptor: Interactive Multi-Resolution Modeling of Biomolecular Assemblies,
Stefan Birmanns and Willy Wriggers,
Long Beach, California. February 2-6, 2008.

Poster presentation: 52th Annual Meeting, Biophysical Society, Interactive Docking of Atomic Structures into 3D Cryo-Electron Microscopy Reconstructions Guided by Global Optimization, Jochen Heyd and Stefan Birmanns Long Beach, California. February 2-6, 2008.

Poster presentation: 52th Annual Meeting, Biophysical Society, Flexible Registration Of Multi-resolution Data By Spatial Interpolation Coupled With Automatic Parameterization Of The Field Of Influence, Mirabela Rusu and Stefan Birmanns, Long Beach, California. February 2-6, 2008.

Invited talk: The 2007 Meeting of the American Crystallographic Association,
Anchor-Point Registration for Multi-Resolution Modeling of Biomolecular Assemblies,
Stefan Birmanns and Willy Wriggers,
Salt Lake City, Utah, July 21-26, 2007.

Poster presentation: Gordon Research Conference on Three-Dimensional Electron Microscopy,
Anchor-Point Registration for Multi-Resolution Modeling of Biomolecular Assemblies,
Stefan Birmanns and Willy Wriggers,
Colby Sawyer College, New Hampshire, June 24-29, 2007.

Poster presentation: 11th Annual Structural Biology Symposium,
Biomolecular Pleiomorphism Probed by Spatial Interpolation,
Mirabela Rusu, Stefan Birmanns and Willy Wriggers.
Galveston, Texas. May 18-19, 2006.

Invited talk: 51th Annual Meeting, Biophysical Society,
Anchor-Point Registration for Multi-Resolution Modeling of Biomolecular Assemblies,
Stefan Birmanns and Willy Wriggers,
Baltimore, Maryland. March 3-7, 2007.

Beta Test

Sculptor is right now in a beta test phase, a final version 1.0 will be made available shortly. If you would like to help and test the software as a beta tester, please contact us.